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For instance, oral delivery of CEA-functionalized AuNPs using enteric-coated capsules has shown successful systemic absorption in mice, with consistent accumulation in liver and spleen tissues and localized immune activation without systemic toxicity

These results demonstrate that the AR-AST System exhibits excellent response linearity and signal stability across different bacterial species and a broad concentration range, providing reliable experimental data for rapid bacterial resistance identification, minimum inhibitory concentration (MIC) determination, and drug efficacy evaluation

Nat Rev Gastroenterol Hepatol (2019) 16(12):71332

doi: 10.1258/acb.2008.008178